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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ERO1LB All Species: 49.09
Human Site: Y304 Identified Species: 72
UniProt: Q86YB8 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86YB8 NP_063944.3 467 53543 Y304 P R R L K N L Y F L Y L I E L
Chimpanzee Pan troglodytes XP_001156276 467 53719 Y304 P R R L K N L Y F L Y L I E L
Rhesus Macaque Macaca mulatta XP_001103965 468 54383 Y305 P R R L K N L Y F L Y L I E L
Dog Lupus familis XP_546074 753 83528 Y590 P R R L K N L Y F L Y L I E L
Cat Felis silvestris
Mouse Mus musculus Q8R2E9 467 53500 Y304 P R R L K N L Y F L Y L I E L
Rat Rattus norvegicus Q8R4A1 464 54000 Y301 P R R L K N L Y F L Y L I E L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512742 679 76557 Y516 P R R L K N L Y F L Y L I E L
Chicken Gallus gallus XP_419554 467 53247 Y304 P R R L K N L Y F L Y L I E L
Frog Xenopus laevis Q6DD71 465 53720 Y303 P K R L R N L Y F I Y L I E L
Zebra Danio Brachydanio rerio Q7T3D1 489 56571 Y296 P K R L R N L Y F L Y L I E L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V3A6 483 55641 Y319 P H W L R N L Y F I Y L I E L
Honey Bee Apis mellifera XP_623933 471 55049 Y312 P N W L K N L Y F T Y L L E L
Nematode Worm Caenorhab. elegans Q7YTU4 478 55136 N298 E G P Q R L R N V Y F I Y L L
Sea Urchin Strong. purpuratus XP_796844 897 101920 N729 E G P I R L K N L Y F T Y L V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9C7S7 469 53812 T301 L R A V T K A T A Y L E Q A E
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q7SEY9 668 75589 F327 E R I S N L Y F N Y A L L T R
Conservation
Percent
Protein Identity: 100 98.5 60 60.2 N.A. 94 59.3 N.A. 63.3 87.5 58.6 52.5 N.A. 46.1 49 40.7 25.8
Protein Similarity: 100 98.9 75 61.3 N.A. 96.5 74.5 N.A. 66.7 92.7 74.9 68 N.A. 63.9 65.8 59.2 35.9
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 100 100 80 86.6 N.A. 73.3 73.3 6.6 0
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 100 100 100 N.A. 86.6 80 26.6 26.6
Percent
Protein Identity: N.A. N.A. N.A. 38.8 N.A. 28.5
Protein Similarity: N.A. N.A. N.A. 57.3 N.A. 39.6
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. 13.3
P-Site Similarity: N.A. N.A. N.A. 13.3 N.A. 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 7 0 0 0 7 0 7 0 7 0 0 7 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 19 0 0 0 0 0 0 0 0 0 0 7 0 75 7 % E
% Phe: 0 0 0 0 0 0 0 7 75 0 13 0 0 0 0 % F
% Gly: 0 13 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 7 7 0 0 0 0 0 13 0 7 69 0 0 % I
% Lys: 0 13 0 0 57 7 7 0 0 0 0 0 0 0 0 % K
% Leu: 7 0 0 75 0 19 75 0 7 57 7 82 13 13 82 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 7 0 0 7 75 0 13 7 0 0 0 0 0 0 % N
% Pro: 75 0 13 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 7 0 0 0 0 0 0 0 0 7 0 0 % Q
% Arg: 0 63 63 0 32 0 7 0 0 0 0 0 0 0 7 % R
% Ser: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 7 0 0 7 0 7 0 7 0 7 0 % T
% Val: 0 0 0 7 0 0 0 0 7 0 0 0 0 0 7 % V
% Trp: 0 0 13 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 7 75 0 25 75 0 13 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _